4.7 Article

Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 94, Pages 11555-11557

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36264c

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Funding

  1. NIH [GM086249]
  2. [CC10492]

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Despite differences in the crystal structures of ice and nucleosides, antifreeze polypeptides (AFPs) have been demonstrated to inhibit nucleation of 5-methyluridine, cytidine, and inosine and modify the crystal growth of the nucleosides efficiently. The molecular recognition repertoire of AFPs has been expanded to non-ice-like crystalline solids.

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