4.7 Article

Metal ion-binding properties of DNA duplexes containing thiopyrimidine base pairs

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 36, Pages 4347-4349

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc15436f

Keywords

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [21350105]
  2. Grants-in-Aid for Scientific Research [21350105] Funding Source: KAKEN

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Thiopyrimidine pairs in DNA duplexes were unexpectedly largely stabilized by complexation with two equivalents of Ag(I) ions and their binding properties were evaluated. The metal ion-binding properties of the thiopyrimidine base pairs differed significantly from those of unpaired bases.

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