4.7 Article

Enantioselective organocatalytic reductive amination of aliphatic ketones by benzothiazoline as hydrogen donor

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 38, Pages 4573-4575

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31486j

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology, Japan
  2. Japan Society for the Promotion of Science
  3. Grants-in-Aid for Scientific Research [23350046] Funding Source: KAKEN

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The chiral phosphoric acid-catalyzed enantioselective reductive amination of aliphatic ketones with aromatic amines was successfully achieved by the use of benzothiazoline as the hydrogen donor. Corresponding chiral aliphatic amines were obtained with excellent enantioselectivities.

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