4.7 Article

Light-triggered reversible assemblies of azobenzene-containing amphiphilic copolymer with beta-cyclodextrin-modified hollow mesoporous silica nanoparticles for controlled drug release

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 80, Pages 10010-10012

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33995a

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Funding

  1. National Natural Science Foundation of China [20902065, 21076134]
  2. Supporting Project for Science and Technology of Jiangsu Province (Industry) [BE2011074]
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
  4. Innovative Research Team of Advanced Chemical and Biological Materials, Suzhou University

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Hollow mesoporous silica nanoparticles (HMSs) were modified by beta-cyclodextrin via a click reaction, an amphiphilic copolymer with a trans-azobenzene structure was then assembled onto beta-cyclodextrin to cover the surface of the HMSs. The prepared nanocomposites can release drugs in a release-stop-release manner by converting light irradiation.

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