Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 11, Pages 1644-1646Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15644f
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Funding
- National Science Foundation [ECCS 0823849]
- Div Of Electrical, Commun & Cyber Sys
- Directorate For Engineering [0823849] Funding Source: National Science Foundation
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Single molecule recognition imaging and dynamic force spectroscopy (DFS) analysis showed strong binding affinity between an aptamer and ricin, which was comparable with antibody-ricin interaction. Molecular simulation showed a ricin binding conformation with aptamers and gave different ricin conformations immobilizing on substrates that were consistent with AFM images.
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