Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 73, Pages 9138-9140Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc00072e
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Funding
- NIH Directors New Innovator Award [1 DP2 OD006499-01]
- King Abdul Aziz City of Science and Technology (KACST)
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Photoactivation using two photons of NIR allows non-invasive biological manipulation. We applied the principle of dendritic amplification to improve the materials' sensitivity to NIR light. Light induced uncaging or release of L-glutamic acid was 2.8 fold higher when incorporating 4-bromo-7-hydroxycoumarin (Bhc) with self-immolative dendrimers compared with Bhc directly conjugated to L-glutamic acid.
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