Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 31, Pages 3763-3765Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc00081d
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Funding
- State Key Laboratory of Natural Medicines [JKGZ201110]
- Fundamental Research Funds for the Central Universities [2011BPY001, JKY2011028, JKZ2009002]
- NSFC [20902111]
- IRT [1193]
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The first palladium-catalyzed direct C5-arylation of azole-4-carboxylates with simple unactivated arenes through double C-H bond cleavage is realized. This protocol provided a straightforward access to diverse 5-arylsubstituted azole-4-carboxylic derivatives with good functional group tolerance.
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