4.7 Article

Thermally induced [3+2] cyclization of aniline-tethered alkylidenecyclopropanes: a facile synthetic protocol of pyrrolo[1,2-a]indoles

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 62, Pages 7696-7698

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33269h

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Funding

  1. Shanghai Municipal Committee of Science and Technology [11JC1402600]
  2. National Basic Research Program of China (973) [2009CB825300]
  3. National Natural Science Foundation of China [21072206, 20472096, 20872162, 20672127, 20732008, 21121062]

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A facile synthetic method of functionalized pyrrolo[1,2-a]indoles has been developed via a thermally-induced ring-opening and cyclization reaction from aniline-tethered alkylidenecyclopropanes with aldehydes.

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