4.7 Article

A novel exonuclease III aided amplification method for sensitive nucleic acid detection based on single walled carbon nanotube induced quenching

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 2, Pages 269-271

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc16127j

Keywords

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Funding

  1. National Natural Science Foundation of China [20805009, 20890022, 21175029]
  2. SRF for ROCS, SEM [B109, 08XD14010]
  3. Shanghai Nature Science Foundation [08ZR1400900]
  4. Young Scientist Foundation of Fudan University [08FQ12]

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We describe herein a novel exonuclease III aided amplification method based on single walled carbon nanotube quenching (EASQ) for sensitive and convenient nucleic acid detection, which enabled 80-fold decrease of detection limit for HIV1 DNA assay compared with no target recycling.

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