4.7 Article

A facile approach for the delivery of inorganic nanoparticles into the brain by passing through the blood-brain barrier (BBB)

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 1, Pages 61-63

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15113d

Keywords

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Funding

  1. NCRC [R15-2004-024-00000-0]
  2. CRI [2010-0018286]
  3. WCU [R32-2009-10217]
  4. BK21 projects of Medical Sciences and Chemistry
  5. Yonsei University College of Medicine [6-2007-0223]

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This study provides an easy and simple method to obtain inorganic nanoparticles that can penetrate the blood-brain barrier, the heavily guarded system in the brain, via cross-linked serum albumin surface coatings. Their intact BBB permeability was confirmed in both in vitro and in vivo tests.

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