Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 34, Pages 4064-4066Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc30259d
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Funding
- University of Warwick
- Warwick Effect Polymers Limited
- RCUK
- BBSRC
- Wellcome Trust
- Advantage West Midlands (AWM) Science City Initiative
- ERDF
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The direct synthesis of dithiophenol maleimide functional polymers by living radical polymerisation is described without the need for protecting group chemistry. The synthesised polymers have been successfully employed as disulfide bridging agents for salmon calcitonin when used in equimolar quantities, negating the requirement for complex purification strategies, traditionally associated with peptide bioconjugation.
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