4.7 Article

A SERS DNAzyme biosensor for lead ion detection

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 15, Pages 4394-4396

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04140h

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Funding

  1. NSF-IDBR
  2. Showalter trust

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SERS biosensor for sensitive and selective detection of lead ions (Pb2+) based on DNAzyme was developed by taking advantage of the specific catalytic reaction of DNAzyme upon binding to Pb2+ ions. Detection was accomplished by SERS nanoprobe labeled with DNA and Raman reporters for signal amplification.

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