Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 18, Pages 5142-5144Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10672d
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Funding
- National Research Foundation of Korea [2010-0-000728]
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An 'ensemble'-based fluoregenic chemodosimeter 1-Cu(II) for detection of thiols is reported. Complex 1-Cu(II) sensitively senses thiols followed by hydrolysis to give a marked fluorescence enhancement over other amino acids at pH 7.4 under aqueous media. Confocal microscopic imaging of complex 1-Cu(II) is also herewith demonstrated for cellular thiol detection in HepG2 cells.
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