Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 8, Pages 2399-2401Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04887a
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Funding
- Shanghai [09JC1404100, NCET-07-0287]
- SKLBE Fund [2060204]
- Fundamental Research Funds for the Central Universities
- [NSF21075040]
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We have developed a novel graphene-based biosensing platform using peptides as probe biomolecules, and demonstrated its feasibility in the application of real-time monitoring of protease activity based on FRET between GO and dye-labeled peptides. This assay allows the rapid and accurate determination of enzyme kinetic parameters as well as inhibition constants.
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