4.7 Article

A near-infrared fluorescent calcium probe: a new tool for intracellular multicolour Ca2+ imaging

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 37, Pages 10407-10409

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc14045k

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Funding

  1. JSPS
  2. Ministry of Education, Culture, Sports, Science and Technology, Japan [20245019]

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We report a novel near-infrared fluorescent calcium probe (KFCA), which has good optical properties such as intense NIR fluorescence emission (670 nm, QY:0.24), excellent ON/OFF ratio (120-fold), and good wavelength-compatibility with visible-light-emissive fluorophores (Fluo-4, DsRed2), and which is applicable for real-time dual-colour intracellular Ca2+ imaging.

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