4.7 Article

A gold(I)-catalyzed intramolecular oxidation-cyclopropanation sequence of 1,6-enynes: a convenient access to [n.1.0]bicycloalkanes

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 39, Pages 11152-11154

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc14788a

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A gold(I)-catalyzed tandem oxidation/cyclopropanation reaction of 1,6-enynes with an external oxidant has been developed. This quite simple and rapid strategy will provide a safe, mild and versatile avenue to numerous carbo-and hetero [n.1.0]bicyclic frameworks.

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