Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 18, Pages 5232-5234Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10659g
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Mesoporous titania nanoparticles (MTNs) with excellent biocompatibility (LC(50) approximate to 400 mu g mL(-1)) and a large surface area (ca. 237.3 m(2) g(-1)) were synthesized and further functionalized with a phosphate-containing fluorescent molecule (i.e. flavin mononucleotide; FMN) and loaded with an anticancer drug (i.e. Doxorubicin) for successful intracellular bioimaging and drug delivery, respectively, in human breast cancer cells BT-20.
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