4.7 Article

DNAzyme crosslinked hydrogel: a new platform for visual detection of metal ions

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 33, Pages 9312-9314

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12290h

Keywords

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Funding

  1. National Basic Research Program of China [2010CB732402, 2007CB935603]
  2. National Science Foundation of China [20805038, 21075104]
  3. Natural Science Foundation of Fujian Province [2008J0107]
  4. Natural Science Foundation of Fujian Province for Distinguished Young Scholar [2010J06004]

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We propose the use of DNAzyme as a crosslinker of hydrogel to develop a catalytic platform for the sensing of metal ions. The DNAzyme crosslinked hydrogel can undergo gel-sol transition in response to Cu2+ ions, which enables sensitive visual detection of Cu2+ by observing the release of pre-trapped AuNPs.

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