Journal
PLASMID
Volume 43, Issue 1, Pages 85-98Publisher
ACADEMIC PRESS INC
DOI: 10.1006/plas.1999.1444
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Funding
- NIDCR NIH HHS [DEW11875] Funding Source: Medline
- NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH [R03DE011875] Funding Source: NIH RePORTER
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We have characterized the promoter regions of the gtfB and gtfC genes from Streptococcus mutans GS-5. Using a plasmid-based reporter system, we discovered that the gtfC promoter is an order of magnitude stronger than the gtfB promoter. In addition, we found that a variety of growth conditions failed to affect or discriminate between the expression of the two promoters. Only during the various phases of growth could we demonstrate significant changes in expression. We conclude that gtfB and gtfC promoters are coordinately expressed, (C) 2000 Academic Press.
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