4.7 Article

From static to dynamic: escaping kinetic traps in hydrazone-based dynamic combinatorial libraries

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 26, Pages 7359-7361

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12268a

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Funding

  1. EPSRC
  2. Gates Cambridge Trust
  3. Danish Research Council for Natural Sciences
  4. Lundbeckfonden
  5. EPSRC [EP/F035888/1] Funding Source: UKRI
  6. Engineering and Physical Sciences Research Council [EP/F035888/1] Funding Source: researchfish

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Thermodynamic control over kinetically-trapped mixtures of hydrazone-based macrocycles is achieved by addition of an aromatic monohydrazide to generate dynamic combinatorial libraries (DCLs) of linear and macrocyclic oligomers.

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