Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 12, Pages 3514-3516Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05265e
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Funding
- A*STAR Cross Council Office (CCO), Singapore [CCOGA02_005_2008]
- National University of Singapore (NUS) [R-143-000-353-101]
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SERS nanotags have been prepared to accomplish the multiplex detection of cancer cells. Herein we evaluated the adequacy of lipoic acid-containing cyanine derivatives (Cy3LA and Cy5LA) to function as multiplex partners with a triphenylmethine Raman reporter (B2LA) under a single excitation wavelength. SERS experiments enabled the multiplex recognition of two different cancer cells with antibody-conjugated nanotags that were derivatized with optimized cyanine and triphenylmethine reporters.
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