4.7 Article

Hydrophilic mesoporous carbon nanoparticles as carriers for sustained release of hydrophobic anti-cancer drugs

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 7, Pages 2101-2103

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04598e

Keywords

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Funding

  1. Shanghai Pujiang Program [09PJ1403000]
  2. Research Fund for the Doctoral Program of Higher Education [20090074120009]
  3. Natural Science Foundation of China [51072053]

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The uniform mesoporous carbon nanoparticles (MCNs) with size below 200 nm and good water dispersibility were successfully synthesized via a combined hydrothermal synthesis and hard templating. The prepared MCNs served as effective carriers for camptothecin which efficiently inhibited the growth of MCF-7 cancer cells after its sustained release therein.

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