Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 12, Pages 3478-3480Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05703g
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Funding
- 863 project [2007AA02Z331]
- SKLBE Fund [2060204]
- Fundamental Research Funds for the Central Universities
- [NSF21075040]
- [09JC1404100]
- [NCET-07-0287]
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Single stranded DNA sequences can be detected by target assisted exonuclease III-catalyzed signal amplification fluorescence polarization (TAECA-FP). The method offers an impressive detection limit of 83 aM within one hour for DNA detection and exhibits high discrimination ability even against a single base mismatch.
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