4.7 Article

Surface glycosylation of polymer membrane by thiol-yne click chemistry for affinity adsorption of lectin

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 13, Pages 3930-3932

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10634a

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Funding

  1. National Natural Science Foundation of China [50933006]
  2. National Basic Research Program of China [2009CB623401]

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We present a novel approach to constructing glycosylated surface for microporous membrane. Carbohydrate derivative can be facilely bound onto the alkyne-modified membrane surface via thiol-yne click chemistry. The glycosylated membrane surface shows an excellent affinity adsorption to lectin on the basis of carbohydrate-protein recognition.

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