4.7 Article

A nanoscale DNA-Au dendrimer as a signal amplifier for the universal design of functional DNA-based SERS biosensors

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 13, Pages 3840-3842

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05133k

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Funding

  1. NSFC [J0830415, 20975034]
  2. National Key Scientific Program of China [2011CB911000]
  3. Program for Changjiang Scholars and Innovative Research Team in University

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The use of a nanoscale DNA-Au dendrimer as a signal amplifier was proposed for the universal design of functional DNA-based ultra-sensitive SERS biosensors. This novel design combines the high specificity of functional DNA with the high sensitivity of surface-enhanced Raman scattering (SERS) spectroscopy, resulting in sensitivity superior to that of previously reported sensors.

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