4.7 Article

Metal-free aerobic oxidative coupling of amines to imines

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 36, Pages 10148-10150

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13202d

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Funding

  1. Peking University, NSFC [20841002, 20801002]

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Oxidative coupling of primary amines to imines is achieved with high to moderate yields by refluxing suspensions of amines and water under one atmosphere dioxygen without any additives. Tandem acid-free aza Diels-Alder reactions for synthesis of N-alkyl-4-pyridones are also accomplished.

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