4.7 Article

A FRET-based indicator for imaging mitochondrial zinc ions

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 42, Pages 11730-11732

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc14580k

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Funding

  1. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM081382] Funding Source: NIH RePORTER
  2. NIGMS NIH HHS [R01 GM081382] Funding Source: Medline

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A strategy based on fluorescence resonance energy transfer (FRET) to transform a red-emitting fluorophore into a ratio-metric indicator for mitochondrial Zn-II is demonstrated.

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