Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 27, Pages 7559-7566Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc11574j
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Funding
- US National Institutes of Health [R01 GM086258]
- New England Regional Center of Excellence for Biodefense and Emerging Infectious Diseases [U54 AI057159]
- Damon Runyon Cancer Research Foundation [DRG-2002-09]
- National Institutes of Health [1K99 GM097096-01]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [U54AI057159] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R00GM097096, K99GM097096, R01GM086258] Funding Source: NIH RePORTER
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The study of bacterial symbionts of eukaryotic hosts has become a powerful discovery engine for chemistry. This highlight looks at four case studies that exemplify the range of chemistry and biology involved in these symbioses: a bacterial symbiont of a fungus and a marine invertebrate that produce compounds with significant anticancer activity, and bacterial symbionts of insects and nematodes that produce compounds that regulate multilateral symbioses.
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