4.7 Article

A highly selective and sensitive on-off sensor for silver ions and cysteine by light scattering technique of DNA-functionalized gold nanoparticles

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 30, Pages 8557-8559

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12377g

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Funding

  1. National Science Foundation for Distinguished Young Scholars of China [20825102]
  2. National Natural Science Foundation of China [20771072]

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DNA-functionalized gold nanoparticles are shown to act as a light-scattering switch. Ag+ ion turns on the switch through the DNA-Au NPs conjugates based on the formation of cytosine-Ag+-cytosine base pairs, whereas cysteine turns off the light-scattering signal because it competitively binds to Ag+

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