4.7 Article

beta-Cyclodextrin conjugated magnetic nanoparticles for diazepam removal from blood

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 27, Pages 7719-7721

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc11855b

Keywords

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Funding

  1. China Ministry of Science and Technology (973 Project) [2009CB930000]
  2. Natural Science Foundation of China [11032012]
  3. Fok Ying Tung Education Foundation [121035]
  4. Natural Science Foundation of Chongqing Municipal Government (CSTC) [2010AB5116]
  5. 111 project [B06023]

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beta-CD conjugated magnetic nanoparticles that serve as a hemoadsorbent for diazepam removal are fabricated. The diazepam is arrested by the conjugated beta-CD and then the adsorbed diazepam is efficiently removed by an external magnetic field. These particles have potential applications in hemoperfusion or separation of other toxins and drugs.

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