4.7 Article

pH-controlled reversible drug binding and release using a cytosine-rich hairpin DNA

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 28, Pages 8043-8045

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12594j

Keywords

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Funding

  1. 973 Project [20011CB936004]
  2. NSFC [20831003, 90813001, 20833006, 90913007, 20903086]
  3. CAS

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Here we report that a cytosine-rich DNA carrier, that oscillates between a hairpin and an i-motif structure in its response to pH variation, can be used as a drug binding and release device.

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