4.7 Article

A two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 34, Pages 9618-9620

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13583j

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Funding

  1. NIGMS NIH HHS [R01 GM079465] Funding Source: Medline
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM079465] Funding Source: NIH RePORTER

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We report a two-photon fluorescent probe (PN1) that can be excited by 750 nm femto-second pulses, shows high photostability and negligible toxicity, and can visualize H2O2 distribution in live cells and tissue by two-photon microscopy.

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