4.7 Article

Metal-free intramolecular oxidative decarboxylative amination of primary alpha-amino acids with product selectivity

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 33, Pages 9513-9515

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12885j

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Funding

  1. Chinese Academy of Sciences
  2. USTC

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A novel metal-free intramolecular oxidative decarboxylative coupling of primary alpha-amino acids with 2-aminobenzoketones under mild and neutral conditions was developed. Different quinazolines can be selectively obtained by various oxidants.

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