Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 29, Pages 8340-8342Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12694f
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Funding
- National Institutes of Health [GM-58160]
- National Science Foundation [CHE 9808061, DBI 9729592]
- Amgen
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM058160] Funding Source: NIH RePORTER
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An orthogonal set of Cu-catalysts for the selective mono-arylation of alkyl aryl diols using aryl iodides is presented. Picolinic acid ligated copper catalyst provided phenol O-arylation only, while alkyl aryl ethers are generated by ligand-free copper catalyst in the presence of 2 equivalents NaOt-Bu.
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