4.7 Article

Hydrophilically stabilized gold nanostars as SERS labels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 14, Pages 4216-4218

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05229a

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Funding

  1. European Union [W2-80111700]
  2. German Research Foundation (DFG) [INST 190/128-1]

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A biocompatible, seed-mediated synthesis of monodisperse similar to 60 nm gold nanostars, followed by hydrophilic stabilization with ethylene glycol-modified Raman reporter molecules, is presented. Their application as SERS labels for imaging of the tumor suppressor p63 in prostate biopsies by immuno-SERS microscopy is demonstrated.

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