4.7 Article

Generation of the CF3 radical from trifluoromethylsulfonium triflate and its trifluoromethylation of styrenes

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 23, Pages 6632-6634

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc11765c

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The CF3 radical was generated from the reaction of S-(trifluoromethyl)diphenylsulfonium triflate with Na2S2O4 or HOCH2-SO2Na under suitable conditions without further reduction. Based on this, a method for the synthesis of alpha-trifluoromethylated ketones has been successfully developed.

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