4.7 Article

Iron-catalyzed direct amination of azoles using formamides or amines as nitrogen sources in air

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 12, Pages 3652-3654

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05811d

Keywords

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Funding

  1. National Science Foundation of China [20972104, 20902062, 20725206]
  2. Program for Changjiang Scholars in China

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A new iron-catalyzed, direct C-H amination of azoles at C2 has been developed by using formamides or amines as nitrogen sources. Imidazole is the only additive in the catalyst system and oxygen in air is employed during the transformation process.

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