Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 1, Pages 573-575Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc02416c
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Funding
- Deutsche Forschungsgemeinschaft [SPP 1179]
- Alfried Krupp von Bohlen und Halbach Foundation
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The N-heterocyclic carbene-catalyzed coupling of several aldehydes with paraformaldehyde is reported, directly providing the corresponding valuable hydroxymethyl ketones. Results of first mechanistic experiments for this remarkably selective transformation are also provided.
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