Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 36, Pages 10136-10138Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13860j
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Funding
- National Science Foundation of China [20932008]
- Ministry of Science and Technology of China [2011CB808600]
- Chinese Academy of Sciences
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The chiral N-heterocyclic carbene bearing a proximal hydroxy group derived from L-pyroglutamic acid was found to be an efficient catalyst for the [3+2] annulation of enals and isatins to give the corresponding spirocyclic oxindolo-gamma-butyrolactones in good yield with good diastereo- and enantioselectivities.
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