Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 23, Pages 6620-6622Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc11363a
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Funding
- National Natural Science Foundation of China [21032005, 20702047]
- Zhejiang Provincial Natural Science Foundation of China [Y4090028, R407106]
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Polysubstituted pyrroles were efficiently synthesized in moderate yields by a one-pot multicomponent reaction starting from primary amines, ethyl glyoxalate and 2-bromoacetophenones in the presence of pyridine in refluxing acetonitrile. This methodology was utilized to synthesize a highly substituted benz[g]indole.
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