4.7 Article

Tetrahedron-structured DNA and functional oligonucleotide for construction of an electrochemical DNA-based biosensor

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 27, Pages 7689-7691

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc11628b

Keywords

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Funding

  1. NSF of China [21075068]
  2. National Basic Research Program of China (973 Program) [2011CB707703, 2007CB914100]
  3. Tianjin Natural Science Foundation [11JCZDJC22200]

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Tetrahedron-structured DNA (ts-DNA) in combination with a functionalized oligonucleotide was used to develop a turn-on biosensor for Hg2+ ions. The ts-DNA provided an improved sensitivity and was used to block the active sites.

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