4.7 Article

A fluorescent turn-on probe for the detection of alkaline phosphatase activity in living cells

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 35, Pages 9825-9827

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13819g

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Funding

  1. Ministry of Knowledge Economy, Republic of Korea
  2. Korea government (MEST) [2010-0017220]

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Fluorescent probe 1, showing a high fluorescence turn-on signal ratio, enables the real-time imaging of endogenous alkaline phosphatase (ALP) activity in living cells, and the fast and quantitative analysis of enzyme activity at the single-cell level.

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