4.7 Article

Facile synthesis of 3,4-dihalofurans via electrophilic iodocyclization

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 15, Pages 4541-4543

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10584a

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Funding

  1. China Scholarship Council (CSC)

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A facile, efficient, and general synthetic method for 3,4-dihalofurans has been developed via the electrophilic iodocyclization of various 4-hydroxy-2-but-2-yn-1-ones. The use of MeOH as a solvent is crucial for the efficient chemoselective synthesis of the corresponding 3,4-dihalofurans.

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