4.7 Article

Multiplexed near-infrared in vivo imaging complementarily using quantum dots and upconverting NaYF4:Yb3+,Tm3+ nanoparticles

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 28, Pages 8022-8024

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12746b

Keywords

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Funding

  1. MOST [20100018467]
  2. Ministry of Health Welfare [A101626]
  3. Priority Research Center through NRF [2010-0029711]
  4. Basic Science Research Programs [20100020649, 20100028014]

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A new multiplexed NIR in vivo imaging is showcased by using quantum dots and NaYF4:Yb3+,Tm3+ nanoparticles. The 'temporal' multiplexing is demonstrated by alternating the excitation wavelengths and unmixing the emissions of different probes. Multiplexed cellular imaging and the cellular trafficking in animal models are shown.

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