Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 1, Pages 532-534Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc02923h
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Funding
- NSF [CHE-0645041]
- Taiwan Merit Scholarship
- Heisig/Gleysteen Program
- NSF through NNIN
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In this work, sub-50 nm pegylated mesoporous silica nanoparticles prepared with hydrothermal treatment are shown to have long-term stability in various media at both room and physiological temperature. Compared to bare mesoporous silica nanoparticles, the highly pegylated mesoporous silica nanoparticles show significantly improved biocompatibility and decreased macrophage uptake, making these nanoparticles viable for in vivo stealth drug delivery applications.
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