Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 16, Pages 4712-4714Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10393h
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Funding
- MEXT(JSPS) KAKENHI [21310140, 21870016, 20611007]
- Naito Foundation
- Inoue Foundation of Science
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A method was developed that uses small molecules as fluorescent probes to detect specific mRNAs. In this approach, the fluorescence of fluorophore-quencher conjugates is restored by the binding of an mRNA aptamer tag to the quencher segment of the molecules. The method allows real-time detection of mRNA transcripts in vitro.
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