Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 3, Pages 1057-1059Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc03624b
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A robust protocol for the CuI-catalysed arylation of amidines is presented. Whilst the initially identified conditions were useful for benzamidine-derived substrates, difficulties were encountered with more complex substrates. This problem was overcome following a change in ligand type, enabling the synthesis of analogues of the chemical tool, blebbistatin.
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