4.7 Article

Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa Lectin I (PA-IL) using a DNA-based carbohydrate microarray

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 31, Pages 8826-8828

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12428e

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Funding

  1. Chinese Scientific Council [ANR-08-BLAN-0114-01]
  2. region Rhone-Alpes
  3. Lyonbiopole
  4. Region Languedoc Roussillon
  5. CNRS

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The binding of seven multivalent glycoconjugates displaying linear or antenna-like structures and different electronic environments were evaluated towards PA-IL on a DNA-based carbohydrate microarray. The affinity can be modulated by the charge and the topology of the galactosylated derivatives.

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