Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 38, Pages 10590-10592Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc12750k
Keywords
-
Categories
Funding
- NIGMS NIH HHS [R01 GM090294] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM090294] Funding Source: NIH RePORTER
Ask authors/readers for more resources
The use of acyl hydrazides as peptoid sub-monomers is investigated. We demonstrate here that azapeptoids derived entirely from acyl hydrazides can be made conveniently and efficiently using standard peptoid sub-monomer chemistry. Structural studies reveal that the main chain amide bond in these molecules predominantly adopts a trans conformation. A high-quality one bead one compound library of tetramers was made by split and pool synthesis and we found that the identity of the molecule on a single bead could be determined by tandem MALDI mass spectrometry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available