4.7 Article

Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 38, Pages 10743-10745

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13984c

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Funding

  1. Core Research for Evolutional Science and Technology (CREST) of JST
  2. MEXT, Japan
  3. Iketani Science and Technology Foundation

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A novel DNA scaffold, called a DNA slit, was designed for the programmed positioning of Au nanoparticles (AuNPs), and various patterns of thiolated DNA slits were constructed. AuNPs were correctly placed at the predesigned positions in the thiolated DNA slits, indicating that the thiolated staples and the slit cavities guide the correct assembly of AuNPs.

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